Talofofo Bay is an inlet on the south-eastern coast of the island of Guam at the mouth of the Talofofo River in the village of Talofofo.
It is notable for being one of Guam's most accessible brown sand beaches. This brown sand is the deposition of silt and sand from the Talofofo River, which provides a strong visual contrast to the white sand composed of ground coralline limestone found on most of the island.
This Bay is off the largest and longest flowing river on Guam, the Talofofo River. This area also has hammerhead sharks, turtles, and other aquatic sea life. Due to the low-lying cliffs that lead into the ocean, sharks can nest their eggs in the side rock pockets of the Bay.